Key West is an island in the Straits of Florida on the North American continent at the southernmost tip of the Florida Keys.

Key West is politically within the limits of the city of Key West, Monroe County, Florida, United States. The city also occupies nearby islands and portions of nearby islands.

The island is about 4 miles (6.4 km) long and 2 miles (3.2 km) wide. In the late 1950s many of the large salt ponds on the eastern side were filled in, nearly doubling the original land mass of the island.

Key West, ca. 1856

In Pre-Columbian times Key West was inhabited by the Calusa people. The first European to visit was Juan Ponce de León in 1521. As Florida became a Spanish colony, a fishing and salvage village with a small garrison was established here.

Cayo Hueso

Cayo Hueso (pronounced ['ka?o'weso]) is the original Spanish name for the island of Key West. Spanish-speaking people today also use the term Cayo Hueso when referring to Key West. It literally means "bone key". It is said that the island was littered with the remains (bones) from an Indian battlefield or burial ground. The most widely accepted theory of how the name changed to Key West is that it is a false-friend anglicization of the word, on the ground that the word "hueso" (pronounced ['weso]) sounds as if it could mean "west" in English.[1] Other theories of how the island was named are that the name indicated that it was the westernmost Key,[2] or that the island was the westernmost Key with a reliable supply of water.

Many businesses on the island use the name, such as Casa Cayo Hueso, Cayo Hueso Resorts, Cayo Hueso Consultants, Cayo Hueso y Habana Historeum, etc.

In 1763, when Great Britain took control of Florida, the community of Spaniards and Native Americans were moved to Havana. Florida returned to Spanish control 20 years later, but there was no official resettlement of the island. Informally the island was used by fishermen from Cuba and from the British Bahamas, who were later joined by others from the United States after the latter nation's independence. While claimed by Spain, no nation exercised de facto control over the community there for some time.